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The Design of Animal Experiments 
      Reducing the Use of Animals in Research through Better Experimental Design

Michael F W Festing
MRC Toxicology Unit, University of Leicester, UK
Philip Overend
GlaxoSmithKline plc, UK
Rose Gaines Das
NIBSC, UK
Mario Cortina Borja
Department of Statistics, University of Oxford, UK
Manuel Berdoy
Oxford University Veterinary Services, UK

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Reviews
Stephen P Pakes, President, International Council for Laboratory Animal Science
As Laboratory Animal Scientists one of our great responsibilities is to help ensure that the 3R's of Russell and Burch are considered by the scientific community when planning and conducting research that requires animals. Dr. Michael Festing and colleagues have devoted considerable effort to this cause. They have focused on the importance, indeed necessity, of good experimental design and statistical analysis in our goal of reducing the number of animals and still providing valid research results. This notion is shared by Laboratory Animal Scientists world wide.The monograph they have prepared, The Design of Animal Experiments is an important resource for Laboratory Animal Scientists and for all scientists who conduct animal research.

Tim Betts, Bioscientific Events
This book meets all our teaching objectives for Module 5 and every one of our delegates will receive a copy. It is clear, concise and readable and will be really useful for a broad range of Biomedical Scientists.

Clare Stanford, RDS News, April 2002
It will be hard to imagine how we managed without this book: I only hope that enough copies have been printed to cope with the certain demand.

Dr Pete Coffey, LASA Newsletter, Summer 2002
This book should be given to al first year postgraduate students embarking on any work involving the use of animals… it does explain in a very accessible way how by designing sensible statistically valid experiments, one can ensure the minimal use of animals in an experiment…I think this text s essential reading for new personal licence holders.

ANZCCART News, June 2002
This excellent little book makes an important practical contribution to researchers…All biomedical researchers, even those who understand statistics, will gain lasting benefit.

Animal Welfare, issue 11/4, Nov 2002
I would recommend this book to everyone involved in the design of animal experiments…For laboratory animal science courses, it would be a useful addition to the required textbooks.

Laboratory Animal Practitioner
This handbook may serve as a useful tool in the training of future scientists on the use of animals in research.

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